UPF3A Antikörper

Produktnummer ABIN7120628

Produktdetails anti-UPF3A Antikörper

Target: UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UPF3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: UPF3 regulator of nonsense transcripts homolog A(yeast)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IHC:1:20-1:200,IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu UPF3A

Target: UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))

Andere Bezeichnung: UPF3A (UPF3A Produkte)

Synonyme: 2600001C03Rik antikoerper, 4930546M19Rik antikoerper, RENT3A antikoerper, UPF3 antikoerper, UPF3A antikoerper, HUPF3A antikoerper, si:dkey-21o13.6 antikoerper, UPF3 regulator of nonsense transcripts homolog A (yeast) antikoerper, UPF3A, regulator of nonsense mediated mRNA decay antikoerper, Upf3a antikoerper, UPF3A antikoerper, upf3a antikoerper

Hintergrund: Synonyms:HUpf3, HUPF3A, RENT3A, UPF3, UPF3A Background:Involved in nonsense-mediated decay(NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex(EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex(including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. However, UPF3A is shown to be only marginally active in NMD as compared to UPF3B. Binds spliced mRNA upstream of exon-exon junctions. In vitro, weakly stimulates translation.

Molekulargewicht: 51 kDa

Gen-ID: 65110

UniProt: Q9H1J1