NCOA4 Antikörper (C-Term)

Produktnummer ABIN2776441

Dieses Anti-NCOA4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NCOA4 in WB. Geeignet für Human, Ratte, Rind (Kuh), Hund, Pferd und Schwein.

Kurzübersicht für NCOA4 Antikörper (C-Term) (ABIN2776441)

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NCOA4 Antikörper

Bindungsspezifität: C-Term

Sequenz: KEVPGTEDRA GKQKFKSPMN TSWCSFNTAD WVLPGKKMGN LSQLSSGEDK

Homologie: Cow: 86%, Dog: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against NCOA4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 614 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NCOA4

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Andere Bezeichnung: NCOA4

Hintergrund: This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.
Alias Symbols: ARA70, DKFZp762E1112, ELE1, PTC3, RFG
Protein Interaction Partner: UBC, AR, RXRA, ATXN2, AKT1, VDR, GTF2B, KAT2B, RNF14, PPARG, NR3C1, ESR1,
Protein Size: 614

Molekulargewicht: 70 kDa

Gen-ID: 8031

NCBI Accession: NM_005437, NP_005428

UniProt: Q13772

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway