ILF2 Antikörper (C-Term)

Produktnummer ABIN2776419

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ILF2 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio) und Meerschweinchen. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für ILF2 Antikörper (C-Term) (ABIN2776419)

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ILF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ILF2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ILF2 Antibody - C-terminal region

Sequenz: HGGFRKILGQ EGDASYLASE ISTWDGVIVT PSEKAYEKPP EKKEGEEEEE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ILF2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ILF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35731-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ILF2 Antikörper (ABIN2776419)

Yamauchi, Nakamura, Hiramoto, Yuri, Yokota, Naitou, Takeuchi, Yamanaka, Kita, Nakahara, Kinoyama, Matsuhisa, Kaneko, Koutoku, Sasamata, Kobori, Katou, Tawara, Kawabata, Furuichi: "Sepantronium bromide (YM155) induces disruption of the ILF3/p54(nrb) complex, which is required for survivin expression." in: Biochemical and biophysical research communications, Vol. 425, Issue 4, pp. 711-6, (2012) (PubMed).

Jiang, Zhou, Moxley, Jarrett: "Purification and identification of positive regulators binding to a novel element in the c-Jun promoter." in: Biochemistry, Vol. 47, Issue 35, pp. 9318-34, (2008) (PubMed).

Details zu ILF2

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Andere Bezeichnung: ILF2

Hintergrund:

Background Information: Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of the ILF2 gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression.

Gene Name: Interleukin enhancer binding factor 2, 45 kDa

Alternative Symbols: NF45, PRO3063

Protein Name: Interleukin enhancer-binding factor 2

Molekulargewicht: 43 kDa

Gen-ID: 3608

NCBI Accession: NP_004506

UniProt: Q12905