KLF4 Antikörper (N-Term)

Produktnummer ABIN2776415

Der Kaninchen Polyklonal anti-KLF4 Antikörper wird verwendet zum Nachweis von KLF4 in Proben von Human, Rind (Kuh), Pferd, Hund, Schaf, Schwein und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für KLF4 Antikörper (N-Term) (ABIN2776415)

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reaktivität: Human, Rind (Kuh), Pferd, Hund, Schaf, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KLF4 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: KLF4 Antibody - N-terminal region

Sequenz: GAACGGSNLA PLPRRETEEF NDLLDLDFIL SNSLTHPPES VAATVSSSAS

Homologie: Cow: 80%, Dog: 87%, Horse: 87%, Human: 100%, Pig: 80%, Rabbit: 85%, Sheep: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against KLF4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KLF4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104053

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu KLF4

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Andere Bezeichnung: KLF4

Hintergrund:

Background Information: The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.

Gene Name: Kruppel-like factor 4 (gut)

Alternative Symbols: EZF, GKLF

Protein Name: Krueppel-like factor 4

Molekulargewicht: 50kDa

Gen-ID: 9314

NCBI Accession: NP_004226

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance