Far Upstream Element (FUSE) Binding Protein 1 (FUBP1) (Middle Region) Antikörper

Details zu Produkt Nr. ABIN2776409
Antigen
Epitop
Middle Region
10
9
7
7
3
3
2
2
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Kaninchen, Ratte (Rattus)
77
37
31
6
6
5
4
4
3
3
3
2
2
1
Wirt
Kaninchen
60
11
7
Klonalität
Polyklonal
Konjugat
Unkonjugiert
6
4
3
3
3
3
2
2
2
2
2
2
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
65
39
16
10
7
6
5
4
2
2
1
1
Optionen
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human FUBP1
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN977133.
Sequenz YYAHYYQQQA QPPPAAPAGA PTTTQTNGQG DQQNPAPAGQ VDYTKAWEEY
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against FUBP1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Antigen
Andere Bezeichnung FUBP1 (FUBP1 Antibody Abstract)
Hintergrund FUBP1 is a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FBP, FUBP
Protein Interaction Partner: UBC, MDM2, EED, DDX19A, NSUN2, PLD3, ARPC2, ACTR2, ACTR3, ARPC4, HIST1H2BO, SH3GL1, RPA1, PPP5C, LGALS1, CNN2, BAG1, ACO1, AARSD1, GRPEL1, NIF3L1, RPRD1B, CD81, ITGA4, FN1, ATF2, AIMP2, VCAM1, DHX36, MRPL32, MRPL38, MRPL41, MRPL2, CERS2, MRPL42, MRPL46, P
Protein Size: 644
Molekulargewicht 67 kDa
Gen-ID 8880
NCBI Accession NM_003902, NP_003893
UniProt Q96AE4
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 644 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Far Upstream Element (FUSE) Binding Protein 1 (FUBP1) (Middle Region) antibody (ABIN2776409) Immunohistochemistry with Human Breast tissue at an antibody concentration of 5.0ug/m...
Image no. 2 for anti-Far Upstream Element (FUSE) Binding Protein 1 (FUBP1) (Middle Region) antibody (ABIN2776409) WB Suggested Anti-FUBP1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Po...
Produkt verwendet in: Milosevic, Bulau, Mortz, Eickelberg: "Subcellular fractionation of TGF-beta1-stimulated lung epithelial cells: a novel proteomic approach for identifying signaling intermediates." in: Proteomics, Vol. 9, Issue 5, pp. 1230-40, 2009 (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, 2007 (PubMed).