KCTD11 Antikörper (N-Term)
Kurzübersicht für KCTD11 Antikörper (N-Term) (ABIN2776370)
Target
Alle KCTD11 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- RLGRLDLPRG YGETALLRAE ADFYQIRPLL DALRELEASQ GTPAPTAALL
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Homologie
- Cow: 100%, Goat: 90%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against KCTD11. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human KCTD11
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 232 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- KCTD11 (Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))
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Andere Bezeichnung
- KCTD11
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Hintergrund
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The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling. Its inactivation might lead to a deregulation of the tumor-promoting Hedgehog pathway in medulloblastoma.
Alias Symbols: C17orf36, MGC129844, REN, REN/KCTD11, KCASH1
Protein Interaction Partner: KCTD11, CUL3, HDAC1,
Protein Size: 232 -
Molekulargewicht
- 26 kDa
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Gen-ID
- 147040
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NCBI Accession
- NM_001002914, NP_001002914
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UniProt
- Q693B1
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Pathways
- Hedgehog Signalweg
Target
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