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ASIC3 Antikörper (N-Term)

Dieses Anti-ASIC3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ASIC3 in WB und IHC. Geeignet für Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Schwein.
Produktnummer ABIN2776167

Kurzübersicht für ASIC3 Antikörper (N-Term) (ABIN2776167)

Target

Alle ASIC3 (ACCN3) Antikörper anzeigen
ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Reaktivität

Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schwein

Wirt

  • 33
  • 3
  • 1
Kaninchen

Klonalität

  • 37
Polyklonal

Konjugat

  • 22
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ASIC3 Antikörper ist unkonjugiert

Applikation

  • 24
  • 19
  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 9
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    VATFLYQVAE RVRYYREFHH QTALDERESH RLIFPAVTLC NINPLRRSRL

    Homologie

    Cow: 80%, Dog: 80%, Guinea Pig: 80%, Horse: 80%, Human: 100%, Mouse: 87%, Pig: 87%, Rabbit: 87%, Rat: 87%

    Produktmerkmale

    This is a rabbit polyclonal antibody against ACCN3. It was validated on Western Blot and immunohistochemistry.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human ACCN3
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 531 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

    Andere Bezeichnung

    ACCN3

    Hintergrund

    ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
    Alias Symbols: ACCN3, TNaC1, DRASIC, SLNAC1
    Protein Interaction Partner: ASIC3, LIN7B, GOPC, INADL, DLG4, MAGI1, ASIC2, STOM, CSNK2A1, PRKACA, STOML1,
    Protein Size: 531

    Molekulargewicht

    58 kDa

    Gen-ID

    9311

    NCBI Accession

    NM_004769, NP_004760

    UniProt

    Q9UHC3
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