ASIC3 Antikörper (N-Term)
Kurzübersicht für ASIC3 Antikörper (N-Term) (ABIN2776167)
Target
Alle ASIC3 (ACCN3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- VATFLYQVAE RVRYYREFHH QTALDERESH RLIFPAVTLC NINPLRRSRL
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Homologie
- Cow: 80%, Dog: 80%, Guinea Pig: 80%, Horse: 80%, Human: 100%, Mouse: 87%, Pig: 87%, Rabbit: 87%, Rat: 87%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ACCN3. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACCN3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 531 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
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Andere Bezeichnung
- ACCN3
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Hintergrund
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ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
Alias Symbols: ACCN3, TNaC1, DRASIC, SLNAC1
Protein Interaction Partner: ASIC3, LIN7B, GOPC, INADL, DLG4, MAGI1, ASIC2, STOM, CSNK2A1, PRKACA, STOML1,
Protein Size: 531 -
Molekulargewicht
- 58 kDa
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Gen-ID
- 9311
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NCBI Accession
- NM_004769, NP_004760
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UniProt
- Q9UHC3
Target
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