GRIK1 Antikörper (Middle Region)
Kurzübersicht für GRIK1 Antikörper (Middle Region) (ABIN2776118)
Target
Alle GRIK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- IQTRWKHPSV DNRDLFYINL YPDYAAISRA VLDLVLYYNW KTVTVVYEDS
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against Grik1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of mouse GRIK1
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))
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Andere Bezeichnung
- Grik1
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Hintergrund
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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG, Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene.
Alias Symbols: GluK1, GluK5, Glur5, Glur-5, D16Ium24, D16Ium24e, Glurbeta1, A830007B11Rik
Protein Size: 589 -
Molekulargewicht
- 64 kDa
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Gen-ID
- 14805
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NCBI Accession
- XM_006522921, XP_006522984
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UniProt
- Q8C825
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Pathways
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
Target
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