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GRIA2 Antikörper (N-Term)
GRIA2
Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Hund
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2776117
Produktdetails anti-GRIA2 Antikörper
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Target
Alle GRIA2 Antikörper anzeigen
GRIA2
(Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
Bindungsspezifität
Alle Epitope für GRIA2 Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für GRIA2 Antikörper
Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Hund
Wirt
Alle Wirte für GRIA2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für GRIA2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für GRIA2 Antikörper
Dieser GRIA2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für GRIA2 Antikörper
Western Blotting (WB)
Sequenz
FTDGDLLKIQ FGGANVSGFQ IVDYDDSLVS KFIERWSTLE EKEYPGAHTT
Homologie
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Produktmerkmale
This is a rabbit polyclonal antibody against GRIA2. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of human GRIA2
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Discover our top product GRIA2 Primärantikörper
Alternativen
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anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (N-Term) antibody
GRIA2
Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Meerschweinchen, Pferd
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu GRIA2
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Target
GRIA2
(Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
Andere Bezeichnung
GRIA2 (GRIA2 Produkte )
Synonyme
GLUR2 antikoerper, GLURB antikoerper, GluA2 antikoerper, GluR-K2 antikoerper, HBGR2 antikoerper, GluR-2 antikoerper, GluR-B antikoerper, Glur-2 antikoerper, Glur2 antikoerper, GluR2 antikoerper, gluR-B antikoerper, glur2a antikoerper, gria2.1 antikoerper, zfGRIA2[a] antikoerper, glur2 antikoerper, glutamate ionotropic receptor AMPA type subunit 2 antikoerper, glutamate receptor, ionotropic, AMPA 2 antikoerper, glutamate receptor, ionotropic, AMPA2 (alpha 2) antikoerper, glutamate receptor, ionotropic, AMPA 2a antikoerper, glutamate receptor, ionotropic, AMPA 2 S homeolog antikoerper, GRIA2 antikoerper, Gria2 antikoerper, gria2a antikoerper, gria2.S antikoerper
Hintergrund
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG, Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. Alias Symbols: GLUR2, GLURB, GluA2, HBGR2, GluR-K2 Protein Size: 730
Molekulargewicht
80 kDa
Gen-ID
2891
NCBI Accession
NM_000826 , NP_000817
UniProt
P42262
Pathways
PI3K-Akt Signalweg
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