PKD2 Antikörper (N-Term)

Produktnummer ABIN2776087

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PKD2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen und Kaninchen.

Kurzübersicht für PKD2 Antikörper (N-Term) (ABIN2776087)

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PKD2 Antikörper

Bindungsspezifität: N-Term

Sequenz: GLRGLWGTRL MEESSTNREK YLKSVLRELV TYLLFLIVLC ILTYGMMSSN

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PKD2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PKD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PKD2

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Andere Bezeichnung: PKD2

Hintergrund: This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.
Protein Interaction Partner: MAGEA8, PLSCR1, KRTAP10-3, KRTAP10-8, KRT40, PKD1, GOLGA2, CANX, ATP1A1, UBC, PACS2, HAX1, TRPC1, TNNI3, PACS1, CD2AP, DIAPH1, TPM1, PKD2, ACTN2,
Protein Size: 646

Molekulargewicht: 71 kDa

Gen-ID: 5311

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity