TRIM3 Antikörper (N-Term)
Kurzübersicht für TRIM3 Antikörper (N-Term) (ABIN2775959)
Target
Alle TRIM3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- TICGAKQKVL QSQLDTLRQG QEHIGSSCSF AEQALRLGSA PEVLLVRKHM
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TRIM3. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 744 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TRIM3 (Tripartite Motif Containing 3 (TRIM3))
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Andere Bezeichnung
- TRIM3
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Hintergrund
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The protein encoded by TRIM3 is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport.
Alias Symbols: BERP, HAC1, RNF22, RNF97
Protein Interaction Partner: CUL3, UBC, HECW2, KIF21B, TNFAIP3, HGS, MYO5A, ACTN4, UBE2D4, UBE2U, UBE2G2, TRIM3, UBE2K,
Protein Size: 744 -
Molekulargewicht
- 81 kDa
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Gen-ID
- 10612
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NCBI Accession
- NM_006458, NP_006449
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UniProt
- Q6ZTE7
Target
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