ATG4B Antikörper (C-Term)

Produktnummer ABIN2775793

Der Kaninchen Polyklonal Anti-ATG4B-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ATG4B in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Kaninchen, Rind (Kuh) und Pferd zu detektieren.

Kurzübersicht für ATG4B Antikörper (C-Term) (ABIN2775793)

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ATG4B Antikörper

Bindungsspezifität: C-Term

Sequenz: LGGALPMFEL VELQPSHLAC PDVLNLSLDS SDVERLERFF DSEDEDFEIL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against APG4B. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human APG4B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 393 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATG4B

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Andere Bezeichnung: APG4B

Hintergrund: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.
Alias Symbols: APG4B, AUTL1
Protein Interaction Partner: SUMO2, MAP1LC3B, MAP1LC3A, BAG3, ATG8, YWHAB, GABARAPL1, SQSTM1, UBC, GABARAPL2, ATG10, ATG3, AMBRA1, GABARAP, CAMKK2, ATG12, ULK1, STK3, KRT4, ANXA1, FBXW11, LINC00341,
Protein Size: 393

Molekulargewicht: 44 kDa

Gen-ID: 23192

NCBI Accession: NM_013325, NP_037457

UniProt: Q9Y4P1

Pathways: Autophagie