RNF2 Antikörper (Middle Region)

Produktnummer ABIN2775704

Der Kaninchen Polyklonal Anti-RNF2-Antikörper wurde für WB validiert. Er ist geeignet, RNF2 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Kaninchen und Schwein zu detektieren.

Kurzübersicht für RNF2 Antikörper (Middle Region) (ABIN2775704)

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RNF2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: NASTHSNQEA GPSNKRTKTS DDSGLELDNN NAAMAIDPVM DGASEIELVF

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against RNF2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RNF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 336 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RNF2

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Andere Bezeichnung: RNF2

Hintergrund: Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by RNF2 is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
Alias Symbols: BAP1, DING, BAP-1, HIPI3, RING2, RING1B
Protein Interaction Partner: BMI1, SCMH1, HIST2H2AC, UBE2D3, AMBRA1, WASH1, BECN1, ATG14, PIK3C3, TARDBP, SNAI1, NEDD8, UBC, EIF3I, ALYREF, RBM5, RCL1, TRIM28, CEBPZ, SUGP2, G3BP1, AKAP9, YAF2, LRPPRC, KIF20A, RAD50, ARPC4, ABCB6, SMC4, ACOT8, HNRNPDL, THOC1, THRAP3, RBM8A, KIAA0020,
Protein Size: 336

Molekulargewicht: 38 kDa

Gen-ID: 6045

NCBI Accession: NM_007212, NP_009143

UniProt: Q99496