CDC23 Antikörper (C-Term)

Produktnummer ABIN2775691

Der Kaninchen Polyklonal anti-CDC23 Antikörper wird verwendet zum Nachweis von CDC23 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für CDC23 Antikörper (C-Term) (ABIN2775691)

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC23 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDC23 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CDC23 Antibody - C-terminal region

Sequenz: DTREEGKALL RQILQLRNQG ETPTTEVPAP FFLPASLSAN NTPTRRVSPL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CDC23. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDC23

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096664

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CDC23

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Andere Bezeichnung: CDC23

Hintergrund:

Background Information: CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Gene Name: Cell division cycle 23 homolog (S. cerevisiae)

Alternative Symbols: APC8, CUT23, ANAPC8

Protein Name: Cell division cycle protein 23 homolog

Molekulargewicht: 65kDa

Gen-ID: 8697

NCBI Accession: NP_004652

UniProt: Q9UJX2

Pathways: Protein targeting to Nucleus