FKBP6 Antikörper (Middle Region)
Kurzübersicht für FKBP6 Antikörper (Middle Region) (ABIN2775685)
Target
Alle FKBP6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- FCALSAEQQD QFPLQKVLKV AATEREFGNY LFRQNRFYDA KVRYKRALLL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against FKBP6. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FKBP6
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 467 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))
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Andere Bezeichnung
- FKBP6
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Hintergrund
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FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
Alias Symbols: FKBP36, MGC87179, PPIase
Protein Interaction Partner: LZTS2, CDK5RAP3, SUMO1P1, CCDC36, CDC37, USP19, PTGES3, VBP1, PFDN2, OSBP, HSP90AB1, HSP90AA1, TINF2, ACD, NME7, CCNK, GAPDH,
Protein Size: 467 -
Molekulargewicht
- 53 kDa
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Gen-ID
- 8468
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NCBI Accession
- NM_006147, NP_003593
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UniProt
- O75344
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Pathways
- M Phase
Target
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