UBE2E1 Antikörper (Middle Region)

Produktnummer ABIN2775676

Der Kaninchen Polyklonal Anti-UBE2E1-Antikörper wurde für WB validiert. Er ist geeignet, UBE2E1 in Proben von Human, Maus, Kaninchen, Hund, Meerschweinchen, Ratte, Pferd, Rind (Kuh) und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für UBE2E1 Antikörper (Middle Region) (ABIN2775676)

Target: UBE2E1 (Ubiquitin-Conjugating Enzyme E2E 1 (UBE2E1))

Reaktivität: Human, Maus, Kaninchen, Hund, Meerschweinchen, Ratte, Pferd, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UBE2E1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: PKGDNIYEWR STILGPPGSV YEGGVFFLDI TFTPEYPFKP PKVTFRTRIY

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against UBE2E1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UBE2E1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 193 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UBE2E1

Target: UBE2E1 (Ubiquitin-Conjugating Enzyme E2E 1 (UBE2E1))

Andere Bezeichnung: UBE2E1

Hintergrund: UBE2E1 catalyzes the covalent attachment of ubiquitin to other proteins. UBE2E1 mediates the selective degradation of short-lived and abnormal proteins.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: UBCH6
Protein Interaction Partner: TRIM33, RNF11, TRIM32, UBC, TRAF6, MID1, TRIM23, XIAP, NHLRC1, ZNRF1, JADE1, RNF26, SLX8, SLX5, MARCH7, UBE2E1, MARCH5, RNF167, UBA1, RNF130, USP7, NEDD4, Rag1, ZNF827, PARK2, BRCA1, RNF122, RNF128, ITCH, TRIM39, RNF20, FBXO2, WWP2, STUB1, TOPORS, TRIM28,
Protein Size: 193

Molekulargewicht: 21 kDa

Gen-ID: 7324

NCBI Accession: NM_003341, NP_003332

UniProt: P51965

Pathways: Ubiquitin Proteasome Pathway