ACLY Antikörper (Middle Region)

Produktnummer ABIN2775558

Der Kaninchen Polyklonal Anti-ACLY-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ACLY in Proben von Human, Maus, Ratte, Schwein, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Schaf, Hund und Pferd zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für ACLY Antikörper (Middle Region) (ABIN2775558)

Target: ACLY (ATP Citrate Lyase (ACLY))

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Schaf, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACLY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ACLY Antikörper

Bindungsspezifität: Middle Region

Sequenz: LRSAYDSTME TMNYAQIRTI AIIAEGIPEA LTRKLIKKAD QKGVTIIGPA

Homologie: Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ACLY. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACLY

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1101 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ACLY Antikörper (ABIN2775558)

Infantino, Iacobazzi, Palmieri, Menga: "ATP-citrate lyase is essential for macrophage inflammatory response." in: Biochemical and biophysical research communications, Vol. 440, Issue 1, pp. 105-11, (2013) (PubMed).

Details zu ACLY

Target: ACLY (ATP Citrate Lyase (ACLY))

Andere Bezeichnung: ACLY

Hintergrund: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acety
Alias Symbols: ACL, ATPCL, CLATP
Protein Interaction Partner: UBC, UBR4, SIRT2, HUWE1, ISG15, KAT2B, SUMO2, SUMO3, STAU1, SUMO1, NEDD8, MDM2, ASB15, WWOX, TRIM25, MAGED2, BAG3, PPP6C, NCL, MCM6, MCM2, KPNA4, KPNA2, PRMT1, CDKN2A, SRRT, UBD, FN1, APP, SHC1, CUL3, CAND1, CUL2, SIRT7, UL27, HDAC5, TERF2, TERF1, GSK3B,
Protein Size: 1101

Molekulargewicht: 121 kDa

Gen-ID: 47

NCBI Accession: NM_001096, NP_001087

UniProt: P53396

Pathways: Warburg Effekt