ESRP2 Antikörper (C-Term)

Produktnummer ABIN2775446

Produktdetails anti-ESRP2 Antikörper

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LLPAARVPAA ATPLAYYPGP ATQLYMNYTA YYPSPPVSPT TVGYLTTPPT

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against Esrp2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 717 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ESRP2

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Andere Bezeichnung: Esrp2 (ESRP2 Produkte)

Synonyme: RBM35B antikoerper, 9530027K23Rik antikoerper, Rbm35b antikoerper, RGD1310855 antikoerper, cb404 antikoerper, fa07a06 antikoerper, rbm35b antikoerper, sb:cb404 antikoerper, zgc:77254 antikoerper, epithelial splicing regulatory protein 2 antikoerper, microRNA 6773 antikoerper, ESRP2 antikoerper, Esrp2 antikoerper, MIR6773 antikoerper, esrp2 antikoerper

Hintergrund: Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Alias Symbols: 9530027K23Rik, Rbm35b
Protein Size: 717

Molekulargewicht: 77 kDa

Gen-ID: 77411

NCBI Accession: NM_176838, NP_789808

UniProt: Q8K0G8