UPB1 Antikörper (Middle Region)

Produktnummer ABIN2775431

Dieses Anti-UPB1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UPB1 in WB. Geeignet für Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Pferd, Kaninchen, Rind (Kuh), Meerschweinchen und Ziege. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für UPB1 Antikörper (Middle Region) (ABIN2775431)

Target: UPB1 (Ureidopropionase, beta (UPB1))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UPB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UPB1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: AVVISNSGAV LGKTRKNHIP RVGDFNESTY YMEGNLGHPV FQTQFGRIAV

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against UPB1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UPB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 384 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-UPB1 Antikörper (ABIN2775431)

Kunicka, Prochazka, Krus, Bendova, Protivova, Susova, Hlavac, Liska, Novak, Schneiderova, Pitule, Bruha, Vycital, Vodicka, Soucek: "Molecular profile of 5-fluorouracil pathway genes in colorectal carcinoma." in: BMC cancer, Vol. 16, Issue 1, pp. 795, (2016) (PubMed).

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Details zu UPB1

Target: UPB1 (Ureidopropionase, beta (UPB1))

Andere Bezeichnung: UPB1

Hintergrund: UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activityThis gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
Alias Symbols: BUP1
Protein Size: 384

Molekulargewicht: 42 kDa

Gen-ID: 51733

NCBI Accession: NM_016327, NP_057411

UniProt: Q9UBR1