ABHD5 Antikörper (N-Term)
Kurzübersicht für ABHD5 Antikörper (N-Term) (ABIN2775424)
Target
Alle ABHD5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- ABHD5 Antibody - N-terminal region
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Sequenz
- NRPVYAFDLL GFGRSSRPRF DSDAEEVENQ FVESIEEWRC ALGLDKMILL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ABHD5. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ABHD5
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8093754
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ABHD5 (Abhydrolase Domain Containing 5 (ABHD5))
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Andere Bezeichnung
- ABHD5
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Hintergrund
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Background Information: ABHD5 belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in ABHD5 gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.
Gene Name: Abhydrolase domain containing 5
Alternative Symbols: CGI58, IECN2, NCIE2
Protein Name: 1-acylglycerol-3-phosphate O-acyltransferase ABHD5
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Molekulargewicht
- 39kDa
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Gen-ID
- 51099
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NCBI Accession
- NP_057090
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UniProt
- Q8WTS1
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Pathways
- Lipid Metabolism
Target
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