nectin-3 Antikörper (Middle Region)

Produktnummer ABIN785184

Produktdetails anti-nectin-3 Antikörper

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser nectin-3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PDSVKKENKN PVNNLIRKDY LEEPEKTQWN NVENLNRFER PMDYYEDLKM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PVRL3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PVRL3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 549 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Andere Bezeichnung: PVRL3 (NECTIN3 Produkte)

Synonyme: PVRL3 antikoerper, CD113 antikoerper, CDW113 antikoerper, NECTIN-3 antikoerper, PPR3 antikoerper, PRR3 antikoerper, PVRR3 antikoerper, 2610301B19Rik antikoerper, 3000002N23Rik antikoerper, 4921513D19Rik antikoerper, AA407785 antikoerper, AU016832 antikoerper, AW538082 antikoerper, nectin cell adhesion molecule 3 antikoerper, poliovirus receptor-related 3 antikoerper, Nectin3 antikoerper, NECTIN3 antikoerper, PVRL3 antikoerper, nectin3 antikoerper

Hintergrund: Nectins (e.g., PVRL1, MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6, MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.
Alias Symbols: CDw113, DKFZP566B0846, FLJ90624, PPR3, PRR3, PVRR3, nectin-3, CD113, CDW113, NECTIN-3
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, KRTAP4-2, RGS20, UBC, BAG3, TIGIT, PVRL2, PVRL1, PARD3, PVR, MLLT4, PVRL3,
Protein Size: 549

Molekulargewicht: 61 kDa

Gen-ID: 25945

NCBI Accession: NM_015480, NP_056295

UniProt: Q9NQS3

Pathways: Cell-Cell Junction Organization