nectin-3 Antikörper (N-Term)

Produktnummer ABIN2775419

Der Kaninchen Polyklonal anti-nectin-3 Antikörper (ABIN2775419) detektiert spezifisch nectin-3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd und Schwein.

Kurzübersicht für nectin-3 Antikörper (N-Term) (ABIN2775419)

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser nectin-3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-nectin-3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: NECTIN3 Antibody - N-terminal region

Sequenz: SGKYICKAVT FPLGNAQSST TVTVLVEPTV SLIKGPDSLI DGGNETVAAI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PVRL3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PVRL3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42446-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Andere Bezeichnung: NECTIN3

Hintergrund:

Background Information: This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.

Gene Name: nectin cell adhesion molecule 3

Alternative Symbols: PPR3, PRR3, CD113, PVRL3, PVRR3, CDW113, NECTIN-3

Protein Name: nectin-3

Molekulargewicht: 61kDa

Gen-ID: 25945

NCBI Accession: NP_056295

UniProt: Q9NQS3

Pathways: Cell-Cell Junction Organization