RHOD Antikörper (N-Term)
Kurzübersicht für RHOD Antikörper (N-Term) (ABIN2775403)
Target
Alle RHOD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- RHOD Antibody - N-terminal region
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Sequenz
- TAAQAAGEEA PPGVRSVKVV LVGDGGCGKT SLLMVFADGA FPESYTPTVF
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Homologie
- Guinea Pig: 79%, Human: 100%, Rat: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against RHOD. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human RHOD
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42413-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain." in: The Journal of biological chemistry, Vol. 282, Issue 51, pp. 37215-24, (2007) (PubMed).
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- RHOD (Ras Homolog Family Member D (RHOD))
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Andere Bezeichnung
- RHOD
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Hintergrund
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Background Information: Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. RHOD binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Ras homolog family member D
Alternative Symbols: Rho, ARHD, RHOM, RHOHP1
Protein Name: Rho-related GTP-binding protein RhoD
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Molekulargewicht
- 23kDa
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Gen-ID
- 29984
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NCBI Accession
- NP_055393
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UniProt
- O00212
Target
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