FADS1 Antikörper (C-Term)

Produktnummer ABIN2775387

Produktdetails anti-FADS1 Antikörper

Target: FADS1 (Fatty Acid Desaturase 1 (FADS1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FADS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: FNDWFSGHLN FQIEHHLFPT MPRHNYHKVA PLVQSLCAKH GIEYQSKPLL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FADS1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FADS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 444 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FADS1

Target: FADS1 (Fatty Acid Desaturase 1 (FADS1))

Andere Bezeichnung: FADS1 (FADS1 Produkte)

Synonyme: D5D antikoerper, FADS6 antikoerper, FADSD5 antikoerper, LLCDL1 antikoerper, TU12 antikoerper, D5FAD antikoerper, 0710001O03Rik antikoerper, A930006B21Rik antikoerper, AI317215 antikoerper, DSD antikoerper, fatty acid desaturase 1 antikoerper, FADS1 antikoerper, LOC483793 antikoerper, Fads1 antikoerper

Hintergrund: FADS1 is a member of the fatty acid desaturase (FADS) family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs.The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1, this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
Alias Symbols: BC269730_2, D5D, FADS6, FADSD5, FLJ90273, LLCDL1, TU12
Protein Interaction Partner: UBC, XRN1, PAAF1, DHCR7,
Protein Size: 444

Molekulargewicht: 49 kDa

Gen-ID: 3992

NCBI Accession: NM_013402, NP_037534

UniProt: O60427

Pathways: Regulation of Lipid Metabolism by PPARalpha