FADS1 Antikörper (N-Term)

Produktnummer ABIN2775386

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FADS1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für FADS1 Antikörper (N-Term) (ABIN2775386)

Target: FADS1 (Fatty Acid Desaturase 1 (FADS1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FADS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FADS1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FADS1 Antibody - N-terminal region

Sequenz: RHPGGSRVIS HYAGQDATDP FVAFHINKGL VKKYMNSLLI GELSPEQPSF

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 83%, Horse: 83%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 83%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FADS1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FADS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42383-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FADS1

Target: FADS1 (Fatty Acid Desaturase 1 (FADS1))

Andere Bezeichnung: FADS1

Hintergrund:

Background Information: FADS1 is a member of the fatty acid desaturase (FADS) family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1, this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Fatty acid desaturase 1

Alternative Symbols: D5D, TU12, FADS6, FADSD5, LLCDL1

Protein Name: Fatty acid desaturase 1

Molekulargewicht: 52kDa

Gen-ID: 3992

NCBI Accession: NP_037534

UniProt: O60427

Pathways: Regulation of Lipid Metabolism by PPARalpha