GREM1 Antikörper (C-Term)

Produktnummer ABIN2775383

Produktdetails anti-GREM1 Antikörper

Target: GREM1 (Gremlin 1 (GREM1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Ziege, Meerschweinchen, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GREM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EEGSFQSCSF CKPKKFTTMM VTLNCPELQP PTKKKRVTRV KQCRCISIDL

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against Grem1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Grem1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 184 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GREM1

Target: GREM1 (Gremlin 1 (GREM1))

Andere Bezeichnung: Grem1 (GREM1 Produkte)

Synonyme: grem1 antikoerper, MGC136702 antikoerper, zgc:136702 antikoerper, GREM1 antikoerper, drm antikoerper, pig2 antikoerper, dand2 antikoerper, ihg-2 antikoerper, gremlin antikoerper, Cktsf1b1 antikoerper, Drm antikoerper, Grem antikoerper, ld antikoerper, gremlin-1 antikoerper, CKTSF1B1 antikoerper, DAND2 antikoerper, DRM antikoerper, GREMLIN antikoerper, IHG-2 antikoerper, cktsf1b1 antikoerper, gremlin 1a, DAN family BMP antagonist antikoerper, gremlin 1, DAN family BMP antagonist antikoerper, gremlin 1 antikoerper, gremlin 1, DAN family BMP antagonist L homeolog antikoerper, grem1a antikoerper, GREM1 antikoerper, LOC662541 antikoerper, grem1 antikoerper, Grem1 antikoerper, grem1.L antikoerper

Hintergrund: Grem1 is a cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. It down-regulates the BMP4 signaling in a dose-dependent manner and acts as inhibitor of monocyte chemotaxis.
Alias Symbols: Cktsf1b1, Drm, ld
Protein Size: 184

Molekulargewicht: 21 kDa

Gen-ID: 23892

NCBI Accession: NM_011824, NP_035954

UniProt: O70326

Pathways: Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location