NAMPT Antikörper (C-Term)

Produktnummer ABIN2775322

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-NAMPT Antikörper (ABIN2775322) detektiert spezifisch NAMPT in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Rind (Kuh), Pferd und Kaninchen.

Kurzübersicht für NAMPT Antikörper (C-Term) (ABIN2775322)

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAMPT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NAMPT Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PBEF1 Antibody - C-terminal region

Sequenz: VTLEEGKGDL EEYGQDLLHT VFKNGKVTKS YSFDEIRKNA QLNIELEAAH

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PBEF1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PBEF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42255-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-NAMPT Antikörper (ABIN2775322)

Xia, Weisenburger, Koch, Burkart, Reifenberg, Förstermann, Li: "Restoration of perivascular adipose tissue function in diet-induced obese mice without changing bodyweight." in: British journal of pharmacology, Vol. 174, Issue 20, pp. 3443-3453, (2017) (PubMed).

Details zu NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Andere Bezeichnung: PBEF1

Hintergrund:

Background Information: PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Gene Name: Nicotinamide phosphoribosyltransferase

Alternative Symbols: VF, PBEF, PBEF1, VISFATIN, 1110035O14Rik

Protein Name: Nicotinamide phosphoribosyltransferase

Molekulargewicht: 54kDa

Gen-ID: 10135

NCBI Accession: NP_005737

UniProt: P43490