Fibrinogen beta Chain Antikörper (Middle Region)

Produktnummer ABIN2775299

Der Kaninchen Polyklonal anti-Fibrinogen beta Chain Antikörper (ABIN2775299) detektiert spezifisch Fibrinogen beta Chain in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Kaninchen, Meerschweinchen und Hund.

Kurzübersicht für Fibrinogen beta Chain Antikörper (Middle Region) (ABIN2775299)

Target: Fibrinogen beta Chain (FGB)

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Meerschweinchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibrinogen beta Chain Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Fibrinogen beta Chain Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: FGB Antibody - middle region

Sequenz: GNDKISQLTR MGPTELLIEM EDWKGDKVKA HYGGFTVQNE ANKYQISVNK

Homologie: Cow: 91%, Dog: 86%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FGB. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FGB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42217-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Andere Bezeichnung: FGB

Hintergrund:

Background Information: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: fibrinogen beta chain

Alternative Symbols: HEL-S-78p

Protein Name: fibrinogen beta chain

Molekulargewicht: 29kDa

Gen-ID: 2244

NCBI Accession: NP_001171670

UniProt: P02675