MAP3K14 Antikörper (N-Term)

Produktnummer ABIN2775274

Der Kaninchen Polyklonal anti-MAP3K14 Antikörper wird verwendet zum Nachweis von MAP3K14 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen und Meerschweinchen. Er wurde validiert für WB.

Kurzübersicht für MAP3K14 Antikörper (N-Term) (ABIN2775274)

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAP3K14 Antikörper

Bindungsspezifität: N-Term

Sequenz: SEAGPAAISI IAQAECENSQ EFSPTFSERI FIAGSKQYSQ SESLDQIPNN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAP3K14. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K14

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 947 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAP3K14

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Andere Bezeichnung: MAP3K14

Hintergrund: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Alias Symbols: FTDCR1B, HS, HSNIK, NIK
Protein Interaction Partner: UBC, TRAF3, TRAF2, BIRC2, TRAF1, IKBKB, HSP90AA1, CHUK, TRAF6, TNAP, PELI3, TRAF5, TANK, NFKB2, ARRB2, ZFP91, EEF1A1, PEBP1, HSP90AB1, CDC37, MAP3K14, EDAR, IKBKAP, RPL6, RPL5, RIPK1, MAP3K7, MAPK3, CASP8, GRB14, GRB10, GRB7, MAP2K4, IKBKG, MAP3K8, RPL4,
Protein Size: 947

Molekulargewicht: 104 kDa

Gen-ID: 9020

NCBI Accession: NM_003954, NP_003945

UniProt: Q99558

Pathways: NF-kappaB Signalweg, T-Zell Rezeptor Signalweg