WRNIP1 Antikörper (N-Term)

Produktnummer ABIN2775244

Der Kaninchen Polyklonal Anti-WRNIP1-Antikörper wurde für WB validiert. Er ist geeignet, WRNIP1 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Saccharomyces cerevisiae und Zebrafisch (Danio rerio) zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für WRNIP1 Antikörper (N-Term) (ABIN2775244)

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WRNIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-WRNIP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: PGAKRRRLSE SSALKQPATP TAAESSEGEG EEGDDGGETE SRESYDAPPT

Homologie: Cow: 79%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 79%, Rat: 100%, Yeast: 77%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against WRNIP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WRNIP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 640 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-WRNIP1 Antikörper (ABIN2775244)

Tsurimoto, Shinozaki, Yano, Seki, Enomoto: "Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 10, Issue 1, pp. 13-22, (2005) (PubMed).

Details zu WRNIP1

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Andere Bezeichnung: WRNIP1

Hintergrund: Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.
Alias Symbols: FLJ22526, RP11-420G6.2, WHIP, bA420G6.2
Protein Interaction Partner: UBC, RNF31, PIN1, ELP2, ELP3, TRIM28, HDAC11, EPAS1, VCP, SRSF4, SMAD2, RAD18, NUP107, WRNIP1, FGFR1OP, POLD1, ABL1, SUMO2, TOLLIP, DDX58, USP11, OSBPL10, USP25, POLD4, POLD2, WRN,
Protein Size: 640

Molekulargewicht: 72 kDa

Gen-ID: 56897

NCBI Accession: NM_130395, NP_569079

UniProt: Q96S55