DHX30 Antikörper (N-Term)

Produktnummer ABIN2775228

Produktdetails anti-DHX30 Antikörper

Target: DHX30 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 30 (DHX30))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHX30 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: AASRDLLKEF PQPKNLLNSV IGRALGISHA KDKLVYVHTN GPKKKKVTLH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DHX30. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DHX30

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1155 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DHX30

Target: DHX30 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 30 (DHX30))

Andere Bezeichnung: DHX30 (DHX30 Produkte)

Synonyme: DHX30 antikoerper, dhx30 antikoerper, DDX30 antikoerper, RETCOR antikoerper, 2810477H02Rik antikoerper, C130058C04Rik antikoerper, Ddx30 antikoerper, HELG antikoerper, Ret-CoR antikoerper, DExH-box helicase 30 antikoerper, DEAH (Asp-Glu-Ala-His) box helicase 30 antikoerper, DEAH-box helicase 30 antikoerper, DEAH-box helicase 30 S homeolog antikoerper, DEAH (Asp-Glu-Ala-His) box polypeptide 30 antikoerper, DHX30 antikoerper, dhx30 antikoerper, dhx30.S antikoerper, Dhx30 antikoerper

Hintergrund: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DHX30 is a member of this family. The protein has 97 % sequence identity with the mouse HELG protein. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The encoded protein has 97 % sequence identity with the mouse HELG protein. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: DDX30, FLJ11214, KIAA0890, Ret-CoR, RETCOR
Protein Interaction Partner: SUMO2, SUMO3, IVNS1ABP, STAU1, GRSF1, UBC, SUMO1, NEDD8, Fbxl16, WWOX, SUZ12, RNF2, EZH2, NEDD4, TARDBP, HNRNPD, EIF2AK2, SKIL, FN1, ESR1, NDUFA2, ILF3, GNAI2, RAB31, GRK5, CAND1, COPS5, CUL1, CUL3, CUL4B, CUL5, SIRT7, HNRNPA1, HDGF, DHX58, OAS3, Sgol2, Y
Protein Size: 1155

Molekulargewicht: 129 kDa

Gen-ID: 22907

NCBI Accession: NM_014966, NP_055781

UniProt: Q7L2E3

Pathways: Chromatin Binding