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RAD54B Antikörper (Middle Region)

Dieses Anti-RAD54B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RAD54B in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen und Meerschweinchen.
Produktnummer ABIN2775216

Kurzübersicht für RAD54B Antikörper (Middle Region) (ABIN2775216)

Target

Alle RAD54B Antikörper anzeigen
RAD54B (DNA repair and recombination protein RAD54B (RAD54B))

Reaktivität

  • 29
  • 19
  • 18
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt

  • 43
  • 1
Kaninchen

Klonalität

  • 43
  • 1
Polyklonal

Konjugat

  • 20
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RAD54B Antikörper ist unkonjugiert

Applikation

  • 30
  • 13
  • 13
  • 11
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    NSLKPLSMSQ LKQWKHFSGD HLNLTDPFLE RITENVSFIF QNITTQATGT

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

    Produktmerkmale

    This is a rabbit polyclonal antibody against RAD54B. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human RAD54B
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 910 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    RAD54B (DNA repair and recombination protein RAD54B (RAD54B))

    Andere Bezeichnung

    RAD54B

    Hintergrund

    RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
    Alias Symbols: FSBP, RDH54
    Protein Interaction Partner: TCEANC, ATPAF2, ANKRD36BP1, ENKD1, MYO15B, GMCL1, RAD54B, CDC23, SUMO1, PRKAA1, FUS, HECW2, PSMA1, RAD51, NUDT18, NIF3L1, TCEB3, COPS6, SUMO2, UBC, WRN, ZNF580, LNX1, TRAPPC6A, RIBC2, CCDC33, UBE2I, GORASP2, DYRK2, DMC1, CSNK1E, CD2BP2,
    Protein Size: 910

    Molekulargewicht

    103 kDa

    Gen-ID

    25788

    NCBI Accession

    NM_012415, NP_036547

    UniProt

    Q9Y620
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