RAD54B Antikörper (C-Term)

Produktnummer ABIN2855606

Produktdetails anti-RAD54B Antikörper

Target: RAD54B (DNA repair and recombination protein RAD54B (RAD54B))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD54B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to Rad54B (RAD54 homolog B (S. cerevisiae))
Rad54B antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human RAD54B. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Molt-4

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-RAD54B Antikörper (ABIN2855606)

Chen, Tsai, Wang, Teng: "SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression." in: Scientific reports, Vol. 7, Issue 1, pp. 3842, (2017) (PubMed).

Details zu RAD54B

Target: RAD54B (DNA repair and recombination protein RAD54B (RAD54B))

Andere Bezeichnung: RAD54 homolog B (RAD54B Produkte)

Synonyme: RAD54B antikoerper, im:7137737 antikoerper, im:7153525 antikoerper, fsbp antikoerper, rdh54 antikoerper, RDH54 antikoerper, E130016E03Rik antikoerper, Fsbp antikoerper, RGD1306507 antikoerper, RAD54 homolog B (S. cerevisiae) antikoerper, RAD54 homolog B L homeolog antikoerper, RAD54B antikoerper, rad54b antikoerper, rad54b.L antikoerper, Rad54b antikoerper

Hintergrund: The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.

Cellular Localization: Nucleus

Gen-ID: 25788

UniProt: Q9Y620, O95073