JMJD2D Antikörper (C-Term)

Produktnummer ABIN2774949

Produktdetails anti-JMJD2D Antikörper

Target: JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JMJD2D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SSTPGPSAQI IHPSNGRRGR GRPPQKLRAQ ELTLQTPAKR PLLAGTTCTA

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against JMJD2D. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human JMJD2D

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 523 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-JMJD2D Antikörper (ABIN2774949)

Kim, Fuchs, Schwartz, Abdelhamid, Etter, Berry, Li, Ihnat, Li, Janknecht: "Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors." in: American journal of translational research, Vol. 6, Issue 3, pp. 236-47, (2014) (PubMed).

Kim, Oh, Shin, Janknecht: "Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D." in: PLoS ONE, Vol. 7, Issue 4, pp. e34618, (2012) (PubMed).

Details zu JMJD2D

Target: JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

Andere Bezeichnung: JMJD2D (KDM4D Produkte)

Synonyme: JMJD2D antikoerper, 4932416A15 antikoerper, Jmjd2d antikoerper, KDM4D antikoerper, lysine demethylase 4D antikoerper, lysine-specific demethylase 4D antikoerper, lysine (K)-specific demethylase 4D antikoerper, KDM4D antikoerper, LOC524768 antikoerper, Kdm4d antikoerper, LOC617971 antikoerper, LOC100067461 antikoerper, LOC698455 antikoerper, LOC100514356 antikoerper

Hintergrund: JMJD2D belongs to JMJD2 family that is consist of four cancer-associated genes
Alias Symbols: JMJD2D
Protein Interaction Partner: HECW2, PPP1CC, CUL4B, TP53, AR, KDM4D,
Protein Size: 523

Molekulargewicht: 59 kDa

Gen-ID: 55693

NCBI Accession: NM_018039, NP_060509

UniProt: Q6B0I6

Pathways: Warburg Effekt