WWP2 Antikörper (Middle Region)

Produktnummer ABIN2774931

Der Kaninchen Polyklonal Anti-WWP2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, WWP2 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd und Schaf zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für WWP2 Antikörper (Middle Region) (ABIN2774931)

Target: WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WWP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-WWP2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: EMKYTSEGVR YFVDHNTRTT TFKDPRPGFE SGTKQGSPGA YDRSFRWKYH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%, Zebrafish: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against WWP2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WWP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 431 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-WWP2 Antikörper (ABIN2774931)

Rougier, van Bemmelen, Bruce, Jespersen, Gavillet, Apothéloz, Cordonier, Staub, Rotin, Abriel: "Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins." in: American journal of physiology. Cell physiology, Vol. 288, Issue 3, pp. C692-701, (2005) (PubMed).

Details zu WWP2

Target: WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))

Andere Bezeichnung: WWP2

Hintergrund: WWP2 is a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. WWP2 contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions.This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: AIP2, WWp2-like
Protein Interaction Partner: LGALS9B, ANKRD44, FBXL18, VPS37C, PABPC1, RUSC1, HNRNPUL1, WWP2, PAIP1, TRAF4, FAM189A2, PDLIM7, EIF3A, WIPF1, UBE2L3, UBC, SNRPC, PTCH1, SMAD6, SMAD3, EZH2, PTEN, UBE2D3, FBXL15, RNF11, ARRDC1, ARRDC4, ARRDC3, VPS11, UBE2G1, UBE2J2, UBE2E3, UBE2E1, UBE2D
Protein Size: 431

Molekulargewicht: 47 kDa

Gen-ID: 11060

NCBI Accession: NM_199424, NP_955456

UniProt: O00308

Pathways: Negative Regulation of Transporter Activity