MCM2 Antikörper (Middle Region)
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- Target Alle MCM2 Antikörper anzeigen
- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MCM2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- NNELLLFILK QLVAEQVTYQ RNRFGAQQDT IEVPEKDLVD KARQINIHNL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MCM2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MCM2
- Top Product
- Discover our top product MCM2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 904 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
- Andere Bezeichnung
- MCM2 (MCM2 Produkte)
- Synonyme
- CG7538 antikoerper, DmMCM2 antikoerper, DmMcm2 antikoerper, DmeMCM2 antikoerper, Dmel\\CG7538 antikoerper, MCM2 antikoerper, MCM2-7 antikoerper, MCM2_DROME antikoerper, McM2 antikoerper, PCR3 antikoerper, dMCM2 antikoerper, l(3)rL074 antikoerper, XMcm2 antikoerper, bm28 antikoerper, ccnl1 antikoerper, cdc19 antikoerper, cdcl1 antikoerper, mitotin antikoerper, cb737 antikoerper, chunp6905 antikoerper, BM28 antikoerper, CCNL1 antikoerper, CDCL1 antikoerper, D3S3194 antikoerper, MITOTIN antikoerper, MCM7 antikoerper, AA959861 antikoerper, AW476101 antikoerper, Mcmd2 antikoerper, mKIAA0030 antikoerper, Minichromosome maintenance 2 antikoerper, minichromosome maintenance complex component 2 antikoerper, minichromosome maintenance complex component 2 L homeolog antikoerper, Mcm2 antikoerper, mcm2 antikoerper, MCM2 antikoerper, mcm2.L antikoerper
- Hintergrund
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This protein is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BM28, CCNL1, CDCL1, D3S3194, KIAA0030, MGC10606, MITOTIN, cdc19
Protein Interaction Partner: HUWE1, MCM6, CHFR, SUMO2, MCMBP, UBC, SUMO1, MDM2, MCM7, MCM4, HSP90AB1, ACLY, PRRC1, HYOU1, CAP1, NCL, POLA1, TONSL, SNF8, ELL, TCEA1, POLR2A, CDK6, CDK4, CDC6, MCM10, ORC6, CCNB2, VCAM1, P2RX4, ORC5, ORC2, MCM5, MCM3, ITGA4, FN1, CSNK2A1, CDKN2A, DBF4,
Protein Size: 904 - Molekulargewicht
- 102 kDa
- Gen-ID
- 4171
- NCBI Accession
- NM_004526, NP_004517
- UniProt
- P49736
- Pathways
- DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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