Annexin A3 Antikörper (N-Term)

Produktnummer ABIN2774839

Der Kaninchen Polyklonal Anti-Annexin A3-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Annexin A3 in Proben von Human, Kaninchen und Pferd zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für Annexin A3 Antikörper (N-Term) (ABIN2774839)

Target: Annexin A3 (ANXA3)

Reaktivität: Human, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Annexin A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Annexin A3 Antikörper

Bindungsspezifität: N-Term

Sequenz: MASIWVGHRG TVRDYPDFSP SVDAEAIQKA IRGIGTDEKM LISILTERSN

Homologie: Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ANXA3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 323 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Annexin A3 Antikörper (ABIN2774839)

Meyer-Schwesinger, Dehde, Klug, Becker, Mathey, Arefi, Balabanov, Venz, Endlich, Pekna, Gessner, Thaiss, Meyer: "Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 6, pp. 3218-29, (2011) (PubMed).

Bianchi, Bombelli, Raimondo, Torsello, Angeloni, Ferrero, Di Stefano, Chinello, Cifola, Invernizzi, Brambilla, Magni, Pitto, Zanetti, Mocarelli, Perego: "Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3." in: The American journal of pathology, Vol. 176, Issue 4, pp. 1660-70, (2010) (PubMed).

Schordan, Schordan, Endlich, Lindenmeyer, Meyer-Schwesinger, Meyer, Giebel, Cohen, Endlich, Maurer: "Alterations of the podocyte proteome in response to high glucose concentrations." in: Proteomics, Vol. 9, Issue 19, pp. 4519-28, (2009) (PubMed).

Seliger, Dressler, Wang, Kellner, Recktenwald, Lottspeich, Marincola, Baumgärtner, Atkins, Lichtenfels: "Combined analysis of transcriptome and proteome data as a tool for the identification of candidate biomarkers in renal cell carcinoma." in: Proteomics, Vol. 9, Issue 6, pp. 1567-81, (2009) (PubMed).

Details zu Annexin A3

Target: Annexin A3 (ANXA3)

Andere Bezeichnung: ANXA3

Hintergrund: The ANXA3 gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
Alias Symbols: ANX3
Protein Interaction Partner: UBC, ATF2, SNAP23, STXBP2, STX4, ANXA11, ANXA4, ISG15, EMG1, IGSF21, UBR1, UNC119, TP53, REG3A,
Protein Size: 323

Molekulargewicht: 36 kDa

Gen-ID: 306

NCBI Accession: NM_005139, NP_005130

UniProt: P12429