SYVN1 Antikörper (Middle Region)

Produktnummer ABIN2774800

Der Kaninchen Polyklonal anti-SYVN1 Antikörper wird verwendet zum Nachweis von SYVN1 in Proben von Human, Maus, Ratte, Pferd, Hund, Rind (Kuh), Meerschweinchen, Kaninchen und Saccharomyces cerevisiae. Er wurde validiert für WB.

Kurzübersicht für SYVN1 Antikörper (Middle Region) (ABIN2774800)

Target: SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))

Reaktivität: Human, Maus, Ratte, Pferd, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYVN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SYVN1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: SYVN1 Antibody - middle region

Sequenz: QGLLPPFPPG MFPLWPPMGP FPPVPPPPSS GEAVAPPSTS AALSRPSGAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SYVN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SYVN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113264

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SYVN1

Target: SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))

Andere Bezeichnung: SYVN1

Hintergrund:

Background Information: SYVN1 is a protein involved in endoplasmic reticulum (ER)-associated degradation. The protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins.This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms.

Gene Name: Synovial apoptosis inhibitor 1, synoviolin

Alternative Symbols: DER3, HRD1

Protein Name: E3 ubiquitin-protein ligase synoviolin

Molekulargewicht: 67kDa

Gen-ID: 84447

NCBI Accession: NP_115807

UniProt: Q86TM6

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling