ITCH Antikörper (N-Term)

Produktnummer ABIN2774796

Produktdetails anti-ITCH Antikörper

Target: ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITCH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QLESEVVTNG ETTCSESASQ NDDGSRSKDE TRVSTNGSDD PEDAGAGENR

Homologie: Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ITCH. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ITCH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 862 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ITCH

Target: ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))

Andere Bezeichnung: ITCH (ITCH Produkte)

Synonyme: AIF4 antikoerper, AIP4 antikoerper, NAPP1 antikoerper, dJ468O1.1 antikoerper, 6720481N21Rik antikoerper, 8030492O04Rik antikoerper, A130065M08 antikoerper, C230047C07Rik antikoerper, itchy E3 ubiquitin protein ligase antikoerper, itchy, E3 ubiquitin protein ligase antikoerper, ITCH antikoerper, Itch antikoerper

Hintergrund: Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like prot
Alias Symbols: AIF4, AIP4, NAPP1, dJ468O1.1
Protein Interaction Partner: GSN, UBE2L3, UBC, ITCH, WWOX, GGA3, UBE2D2, PTCH1, ATXN3, HTT, EGFR, SMAD6, DTX3L, CXCR4, LATS1, POLR2A, HNRNPL, EWSR1, RPAP2, CPSF7, RPAP3, UBAP2, PABPC1, DAZAP1, WBP2, SMARCE1, SMARCC2, SMARCC1, POLR2E, POLR2C, SPG20, HNRNPUL1, UBAP2L, URI1, ARID1A, SF1
Protein Size: 862

Molekulargewicht: 99 kDa

Gen-ID: 83737

NCBI Accession: NM_031483, NP_113671

UniProt: A9Z1X3

Pathways: Activation of Innate immune Response, CXCR4-mediated Signaling Events