FBXO11 Antikörper (Middle Region)

Produktnummer ABIN2774788

Dieses Anti-FBXO11-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FBXO11 in WB und ChIP. Geeignet für Human, Maus, Ratte, Pferd, Zebrafisch (Danio rerio), Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für FBXO11 Antikörper (Middle Region) (ABIN2774788)

Target: FBXO11 (F-Box Protein 11 (FBXO11))

Reaktivität: Human, Maus, Ratte, Pferd, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Produktdetails anti-FBXO11 Antikörper

Bindungsspezifität: Middle Region

Sequenz: HDVEFIRHDR FFCDCGAGTL SNPCTLAGEP THDTDTLYDS APPIESNTLQ

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXO11. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO11

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 843 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXO11

Target: FBXO11 (F-Box Protein 11 (FBXO11))

Andere Bezeichnung: FBXO11

Hintergrund: FBXO11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for FBXO11.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: FBX11, FLJ12673, MGC44383, PRMT9, UG063H01, VIT1, UBR6
Protein Interaction Partner: SKP1, ERN1, DTL, CUL1, EED, UBC, NEDD8, COPS5, COPS6, ELAVL1, USP16, HDAC6, BCL6, RBX1, TP53,
Protein Size: 843

Molekulargewicht: 94 kDa

Gen-ID: 80204

NCBI Accession: NM_025133, NP_079409

UniProt: Q6DF73

Pathways: Sensory Perception of Sound