RNF43 Antikörper (Middle Region)
Kurzübersicht für RNF43 Antikörper (Middle Region) (ABIN2774743)
Target
Alle RNF43 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- DFDPLVYCSP KGDPQRVDMQ PSVTSRPRSL DSVVPTGETQ VSSHVHYHRH
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Homologie
- Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against RNF43. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human RNF43
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 783 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95." in: Experimental cell research, Vol. 314, Issue 7, pp. 1519-28, (2008) (PubMed).
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A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95." in: Experimental cell research, Vol. 314, Issue 7, pp. 1519-28, (2008) (PubMed).
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- RNF43 (Ring Finger Protein 43 (RNF43))
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Andere Bezeichnung
- RNF43
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Hintergrund
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RNF43 is a HAP95 (AKAP8L) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer.
Alias Symbols: DKFZp781H02126, DKFZp781H0392, FLJ20315, MGC125630, RNF124, URCC
Protein Interaction Partner: RSPO1, SFPQ, NONO, HECW1, TP53, UBE2D4, KDM5B, UBE2E3, UBE2N, UBE2E1, UBE2D3, UBE2D2, UBE2D1, AKAP8L, UBC,
Protein Size: 783 -
Molekulargewicht
- 86 kDa
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Gen-ID
- 54894
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NCBI Accession
- NM_017763, NP_060233
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UniProt
- Q68DV7
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Pathways
- WNT Signalweg
Target
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