EXOC2 Antikörper (N-Term)

Produktnummer ABIN2774594

Dieses Anti-EXOC2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EXOC2 in WB. Geeignet für Maus, Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für EXOC2 Antikörper (N-Term) (ABIN2774594)

Target: EXOC2 (Exocyst Complex Component 2 (EXOC2))

Reaktivität: Maus, Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EXOC2 Antikörper

Bindungsspezifität: N-Term

Sequenz: MLDLDNDTRP SVLGHLSQTA SLKRGSSFQS GRDDTWRYKT PHRVAFVEKL

Homologie: Cow: 85%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EXOC2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human EXOC2

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EXOC2

Target: EXOC2 (Exocyst Complex Component 2 (EXOC2))

Andere Bezeichnung: EXOC2

Hintergrund: The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.
Alias Symbols: SEC5, Sec5p, SEC5L1
Protein Size: 519

Molekulargewicht: 57 kDa

Gen-ID: 55770

NCBI Accession: NM_018303, NP_060773

UniProt: Q96KP1

Pathways: Peptide Hormone Metabolism, Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis