LGMN Antikörper (Middle Region)
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- Target Alle LGMN Antikörper anzeigen
- LGMN (Legumain (LGMN))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Schaf, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LGMN Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- ESSYACYYDE KRSTYLGDWY SVNWMEDSDV EDLTKETLHK QYHLVKSHTN
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against LGMN. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human LGMN
- Top Product
- Discover our top product LGMN Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 433 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LGMN (Legumain (LGMN))
- Andere Bezeichnung
- LGMN (LGMN Produkte)
- Synonyme
- AEP antikoerper, LGMN1 antikoerper, PRSC1 antikoerper, AI746452 antikoerper, AU022324 antikoerper, Prsc1 antikoerper, MGC64351 antikoerper, cb173 antikoerper, cb460 antikoerper, sb:cb173 antikoerper, zgc:76953 antikoerper, wu:fa98g05 antikoerper, wu:fj92g08 antikoerper, lgmn antikoerper, MGC88980 antikoerper, DELTA VACUOLAR PROCESSING ENZYME antikoerper, DELTAVPE antikoerper, delta vacuolar processing enzyme antikoerper, legumain antikoerper, legumain L homeolog antikoerper, delta vacuolar processing enzyme antikoerper, Legumain antikoerper, LGMN antikoerper, Lgmn antikoerper, lgmn.L antikoerper, lgmn antikoerper, DELTA-VPE antikoerper, MBOO_RS07785 antikoerper, Odosp_3582 antikoerper, LOC569153 antikoerper
- Hintergrund
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This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined.
Alias Symbols: AEP, LGMN1, PRSC1
Protein Interaction Partner: USP17L2, TRAF6, USP17L9P, SUMO1, UBC, NEDD8, LAMC3, ACIN1, IGF2BP3, HNRNPR, FBXO6, ISG15, LGMN,
Protein Size: 433 - Molekulargewicht
- 48 kDa
- Gen-ID
- 5641
- NCBI Accession
- NM_005606, NP_005597
- UniProt
- Q99538
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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