RGR Antikörper (N-Term)

Produktnummer ABIN2774370

Produktdetails anti-RGR Antikörper

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Rind (Kuh), Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SLLRVSHRRW PYGSDGCQAH GFQGFVTALA SICSSAAIAW GRYHHYCTRS

Homologie: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 100%, Rat: 86%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against RGR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 295 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RGR

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Andere Bezeichnung: RGR (RGR Produkte)

Synonyme: RP44 antikoerper, MGC84794 antikoerper, RGR antikoerper, rgr antikoerper, zgc:110660 antikoerper, rgr2 antikoerper, wu:fb64c10 antikoerper, zgc:109930 antikoerper, retinal G protein coupled receptor antikoerper, retinal G protein coupled receptor L homeolog antikoerper, retinal G protein coupled receptor a antikoerper, retinal G protein coupled receptor b antikoerper, RGR antikoerper, Rgr antikoerper, rgr.L antikoerper, rgr antikoerper, rgra antikoerper, rgrb antikoerper

Hintergrund: This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively).
Alias Symbols: RP44
Protein Interaction Partner: KIAA1279, RDH5,
Protein Size: 295

Molekulargewicht: 32 kDa

Gen-ID: 5995

NCBI Accession: NM_002921, NP_002912