FGF8 Antikörper (C-Term)

Produktnummer ABIN2774365

Der Kaninchen Polyklonal anti-FGF8 Antikörper wird verwendet zum Nachweis von FGF8 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Schwein, Pferd und Schaf. Er wurde validiert für WB.

Kurzübersicht für FGF8 Antikörper (C-Term) (ABIN2774365)

Target: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Schwein, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FGF8 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: FGF8 Antibody - C-terminal region

Sequenz: EGWYMAFTRK GRPRKGSKTR QHQREVHFMK RLPRGHHTTE QSLRFEFLNY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 75%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 75%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FGF8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63185-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FGF8

Target: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Andere Bezeichnung: FGF8

Hintergrund:

Background Information: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.

Gene Name: Fibroblast growth factor 8 (androgen-induced)

Alternative Symbols: HH6, AIGF, KAL6, FGF-8, HBGF-8

Protein Name: Fibroblast growth factor 8

Molekulargewicht: 22kDa

Gen-ID: 2253

NCBI Accession: NP_006110

UniProt: P55075

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Dopaminergic Neurogenesis