VPS4B Antikörper (N-Term)

Produktnummer ABIN2774320

Dieses Anti-VPS4B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von VPS4B in WB. Geeignet für Human, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen und Rind (Kuh).

Kurzübersicht für VPS4B Antikörper (N-Term) (ABIN2774320)

Target: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Reaktivität: Human, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-VPS4B Antikörper

Bindungsspezifität: N-Term

Sequenz: EKLKEYLKNK EKKAQKPVKE GQPSPADEKG NDSDGEGESD DPEKKKLQNQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against VPS4B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 444 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu VPS4B

Target: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Andere Bezeichnung: VPS4B

Hintergrund: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18, the gene for the other resides on chromosome 16.
Alias Symbols: MIG1, SKD1, SKD1B, VPS4-2
Protein Interaction Partner: ZFYVE19, CHMP5, UBC, HTRA2, CHMP4A, TTLL12, AHCYL1, SSSCA1, YAP1, UBE4B, PDCD6IP, USP34, VPS26A, USP8, ZPR1, NUP214, TYMS, RAB5B, IGBP1, TTC9C, ZNF585B, UBQLN4, UBXN1, UBQLN1, CUL3, CHMP2A, CHMP1A, ELAVL1, BABAM1, CHMP1B, VPS4A, VPS4, LIP5,
Protein Size: 444

Molekulargewicht: 49 kDa

Gen-ID: 9525

NCBI Accession: NM_004869, NP_004860

UniProt: O75351

Pathways: Microtubule Dynamics, CXCR4-mediated Signaling Events