CD70 Antikörper (N-Term)

Produktnummer ABIN2774311

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD70 in WB. Er zeigt eine Reaktivität gegenüber Human, Rind (Kuh), Kaninchen, Pferd und Meerschweinchen.

Kurzübersicht für CD70 Antikörper (N-Term) (ABIN2774311)

Target: CD70 (CD70 Molecule (CD70))

Reaktivität: Human, Rind (Kuh), Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD70 Antikörper

Bindungsspezifität: N-Term

Sequenz: VICLVVCIQR FAQAQQQLPL ESLGWDVAEL QLNHTGPQQD PRLYWQGGPA

Homologie: Cow: 85%, Guinea Pig: 85%, Horse: 77%, Human: 100%, Rabbit: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CD70. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 193 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Alias Symbols: CD27L, CD27LG, TNFSF7
Protein Interaction Partner: UBC, CD27, ELAVL1,
Protein Size: 193

Molekulargewicht: 21 kDa

Gen-ID: 970

NCBI Accession: NM_001252, NP_001243

UniProt: P32970

Pathways: Cancer Immune Checkpoints