FDPS Antikörper (C-Term)

Produktnummer ABIN2774296

Dieses Anti-FDPS-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FDPS in WB und IHC. Geeignet für Human, Ratte, Maus, Hund, Pferd, Schwein, Kaninchen, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für FDPS Antikörper (C-Term) (ABIN2774296)

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Reaktivität: Human, Ratte, Maus, Hund, Pferd, Schwein, Kaninchen, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FDPS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FDPS Antikörper

Bindungsspezifität: C-Term

Sequenz: VKYKTAFYSF YLPIAAAMYM AGIDGEKEHA NAKKILLEMG EFFQIQDDYL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FDPS. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 353 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FDPS

Target: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Andere Bezeichnung: FDPS

Hintergrund: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FPPS, FPS
Protein Interaction Partner: UBC, SUMO2, NME1, IDH1, ADSS, NME1-NME2, STAMBP, TALDO1, SORD, PLS3, EGFR, EIF4ENIF1, ATXN1, FGFR1,
Protein Size: 353

Molekulargewicht: 38 kDa

Gen-ID: 2224

NCBI Accession: NM_001135822, NP_001129294

UniProt: P14324

Pathways: Regulation of Muscle Cell Differentiation