MYOC Antikörper (N-Term)

Produktnummer ABIN2774268

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MYOC in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Meerschweinchen.

Kurzübersicht für MYOC Antikörper (N-Term) (ABIN2774268)

Target: MYOC (Myocilin (MYOC))

Reaktivität: Human, Ratte, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYOC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MYOC Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MYOC Antibody - N-terminal region

Sequenz: QLTLDQAARP QETQEGLQRE LGTLRRERDQ LETQTRELET AYSNLLRDKS

Homologie: Guinea Pig: 86%, Human: 100%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against MYOC. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human MYOC

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59771-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MYOC

Target: MYOC (Myocilin (MYOC))

Andere Bezeichnung: MYOC

Hintergrund:

Background Information: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Gene Name: myocilin, trabecular meshwork inducible glucocorticoid response

Alternative Symbols: GPOA, JOAG, TIGR, GLC1A, JOAG1

Protein Name: myocilin

Molekulargewicht: 37kDa

Gen-ID: 4653

NCBI Accession: NP_000252

UniProt: Q99972