MYOC Antikörper (AA 183-294)

Produktnummer ABIN7160496

Produktdetails anti-MYOC Antikörper

Target: MYOC (Myocilin (MYOC))

Bindungsspezifität: AA 183-294

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYOC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Myocilin protein (183-294AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MYOC

Target: MYOC (Myocilin (MYOC))

Andere Bezeichnung: MYOC (MYOC Produkte)

Synonyme: MYOC antikoerper, MGC136645 antikoerper, zgc:136645 antikoerper, AI957332 antikoerper, GLC1A antikoerper, TIGR antikoerper, GPOA antikoerper, JOAG antikoerper, JOAG1 antikoerper, myocilin antikoerper, Tigr antikoerper, myocilin antikoerper, MYOC antikoerper, myoc antikoerper, Myoc antikoerper

Hintergrund:

Background: Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling. Plays a role in bone formation and promotes osteoblast differentiation in a dose-dependent manner through mitogen-activated protein kinase signaling. Mediates myelination in the peripheral nervous system through ERBB2/ERBB3 signaling. Plays a role as a regulator of muscle hypertrophy through the components of dystrophin-associated protein complex. Involved in positive regulation of mitochondrial depolarization. Plays a role in neurite outgrowth. May participate in the obstruction of fluid outflow in the trabecular meshwork.

Aliases: GLC1A antibody, GPOA antibody, JOAG antibody, JOAG1 antibody, Mutated trabecular meshwork-induced glucocorticoid response protein antibody, MYOC antibody, MYOC_HUMAN antibody, Myocilin antibody, Myocilin, trabecular meshwork inducible glucocorticoid antibody, TIGR antibody, Trabecular meshwork induced glucocorticoid response protein antibody, Trabecular meshwork-induced glucocorticoid response protein antibody

UniProt: Q99972